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Common developmental condition linked to higher risk of Parkinson's-related disorders

Older adults diagnosed with autism face a significantly higher risk of developing Parkinson’s disease-related movement disorders compared to the general population, according to a large new study published in the journal Autism.

Researchers analyzed Medicare and Medicaid claims data covering nearly 57 million Americans aged 45 and older between 2017 and 2019.

Individuals on the spectrum, as well as those with intellectual disabilities, were diagnosed with parkinsonism at much higher rates than those without autism.

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Parkinsonism refers to a range of neurological conditions characterized by certain movement symptoms, including tremors, muscle rigidity, balance difficulties and slowed voluntary movement, according to the Parkinson’s Foundation.

While earlier research suggested an overlap between autism and motor decline later in life, it was unclear whether those problems stemmed from the condition or from antipsychotic medications, which are widely known to trigger Parkinson’s-like symptoms as a secondary side effect.

To determine whether medications explained the link, researchers excluded people who took antipsychotics from the analysis. They still found higher rates of Parkinson’s-related diagnoses in neurodivergent populations.

In the general population control group, the prevalence of parkinsonism was roughly 1.57%. The prevalence rose to 3.83% among adults with autism alone, 4.32% for those with an intellectual disability alone, and 4.86% among individuals diagnosed with both autism and an intellectual disability.

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"A critically important new contribution of this study is increased incidence rates of parkinsonism for autistic people in middle and older adulthood, which suggests that these cases aren’t simply a byproduct of lifelong motor challenges," Greg Wallace, lead author and a professor in the Department of Speech, Language and Hearing Sciences at The George Washington University in Washington, D.C., said in a press release.

The study represents the first time scientists have tracked the incidence rate, or the risk of newly emerging cases over time, among older autistic individuals.

"It is therefore important for clinicians to establish clear baselines of motor skills and challenges during adulthood that can be tracked over time," Wallace added.

Dr. Lee Murray, a neurologist based in Jackson, Tennessee, said this study clarifies previous research that suggested patients with autism are at a higher risk of having Parkinson's.

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"This study takes into account the use of antipsychotic medications that can cause a Parkinson's look (resting tremor, stiffness, shuffled gait, stooped posture, softened voice), which is a different pathology than stereotypical or idiopathic Parkinson's disease," Murray, who was not involved in the study, told Fox News Digital.

"This study showed patients with autism that was associated with intellectual disability seem to have the greatest association with concomitant Parkinson's."

The neurologist cautioned that autism encompasses a wide range of symptoms and severity, so the findings don't mean that people with milder cases face a significantly higher risk of Parkinson’s disease.

"It certainly is an interesting correlation, although it does not imply that someone with autism is certain to develop Parkinson's," Murray added.

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"From a clinical perspective, it's helpful to review medications with the autistic patient's physicians and, if possible, try to avoid medications that may cause a Parkinson's appearance."

Despite the scope of the data, the authors noted several key limitations of using insurance records.

The investigation relied on billing and diagnostic codes submitted through Medicare and Medicaid, which can contain errors or reflect differences in how clinics and medical providers diagnose conditions.

The reliance on claims data also means researchers could not assess the severity of individual motor symptoms or examine the role of lifestyle factors, genetics and family history, they noted.

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Additionally, the data only captured adults who were enrolled in public insurance programs, potentially leaving out older individuals who rely strictly on private health insurance.

Because people on the autism spectrum may already struggle with coordination, repetitive behaviors or executive functioning challenges, experts say early indicators of Parkinson’s disease can be missed or mistaken, potentially delaying essential care.

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"Patients with autism can have atypical movements that can be misdiagnosed as Parkinson's if the examiner is not accustomed to diagnosing it," Murray confirmed.

The researchers emphasized the need for physicians, long-term care facilities and family caregivers to closely monitor older autistic patients for motor decline so interventions can begin as early as possible.

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Love it or loathe it, AI is birthing a golden age of science

It’s almost hard to remember, but just a few years ago, a lot of very smart people thought that science was in terminal decline. Respected researchers were writing papers with titles like “Are Ideas Getting Harder to Find?”, “Papers and patents are becoming less disruptive over time”, and “Slowed canonical progress in large fields of […]

The post Love it or loathe it, AI is birthing a golden age of science appeared first on Asia Times.

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FOX News Media teams up with Breast Cancer Research Foundation

FOX News Media teamed up with the Breast Cancer Research Foundation (BCRF) Thursday for a special panel highlighting advances in breast cancer research and treatment while urging women to take an active role in their healthcare. 

The event, held at Fox News headquarters in New York City during Breast Cancer Awareness Month, featured Kat Timpf, the "Gutfeld!" co-host and breast cancer survivor, alongside Dr. Priya Malhotra, director of research impact at BCRF.

Speaking with Fox News Digital after the panel, Timpf emphasized that while breast cancer awareness is widespread, misconceptions about the disease persist and may discourage people from asking important questions about their health.

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"There is also so much that people don’t know. It can happen at any age, without genetic markers. I would know that," Timpf told Fox News Digital. "Talking about it is always helpful because it removes a lot of the stigma, and it makes you feel like you can ask these questions to your doctor."

Timpf was diagnosed with Stage 0 ductal carcinoma in situ (DCIS) in February 2025, just 15 hours before giving birth to her first child. She announced the news on social media days later, writing what she called an "unconventional birth announcement."

"Last week, I welcomed my first child into the world. About fifteen hours before I went into labor, I was diagnosed with breast cancer," Timpf wrote on X at the time.

"Now, before you worry, my doctor says it’s stage 0 and is confident that it almost certainly hasn’t spread. Or, as I’ve explained to the few people I’ve managed to tell about it so far: Don’t freak out. It’s just, like, a LITTLE bit of cancer."

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Throughout her breast cancer experience, Timpf leaned on her signature humor, a coping mechanism she said helped her through some of the most difficult moments of her diagnosis and recovery.

"Humor is how I've gotten through every hard thing that's ever happened to me," Timpf said. "I was making jokes the day I was diagnosed about getting huge replacement [implants] and stuff like that. That's just how I do things because I feel like when you say that you can't joke about a subject, you're giving it even more power over you than it already has.

"For me, making jokes about a subject is a way to instead feel power over the things that are threatening to take you down."

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Timpf's central message to women was to take an active role in their healthcare, stay on top of recommended screenings and speak up when something doesn't feel right.

"Your own health is up to you. So, you have to make sure you pay attention and ask your doctor questions," Timpf said. "Don't think it can't happen to you because I thought that, and I was wrong."

Breast cancer is the most common cancer among women in the U.S. and worldwide, with approximately one in eight U.S. women expected to develop invasive breast cancer during their lifetime, according to the Breast Cancer Research Foundation.

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While breast cancer has historically been more commonly diagnosed in older women, rates are rising among younger women, including those under 40, before routine mammograms are generally recommended for women at average risk.

Dr. Malhotra emphasized that while breast cancer diagnoses in younger women account for a relatively small share of cases, the impact is profound.

"Incidence of breast cancer is rising in younger women," Dr. Malhotra told Fox News Digital.

"Maybe 10% of breast cancers are in younger women," she added. "But still, if you're one of the 10%, it's crushing."

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Dr. Malhotra, who previously served on the faculty at Georgetown University, now works at BCRF to help advance breast cancer research. She highlighted the growing number of targeted treatments developed in recent decades.

"In 1977, we had one targeted treatment for breast cancer. Twenty years later, we had two," Dr. Malhotra explained. "Fast forward to today, we have over 30 targeted treatments, 19 in the last decade alone. So, it’s moving very quickly, and we're proud to say that our investigators are involved in all of those, getting them across the finish line."

She also stressed the importance of recognizing changes in one's body and speaking up during medical appointments.

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"My biggest thing is to know your body because if you feel that something is out of whack — even if you think it's minor — it’s worth it to talk to your doctor about," Dr. Malhotra said.

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