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Common developmental condition linked to higher risk of Parkinson's-related disorders

Older adults diagnosed with autism face a significantly higher risk of developing Parkinson’s disease-related movement disorders compared to the general population, according to a large new study published in the journal Autism.

Researchers analyzed Medicare and Medicaid claims data covering nearly 57 million Americans aged 45 and older between 2017 and 2019.

Individuals on the spectrum, as well as those with intellectual disabilities, were diagnosed with parkinsonism at much higher rates than those without autism.

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Parkinsonism refers to a range of neurological conditions characterized by certain movement symptoms, including tremors, muscle rigidity, balance difficulties and slowed voluntary movement, according to the Parkinson’s Foundation.

While earlier research suggested an overlap between autism and motor decline later in life, it was unclear whether those problems stemmed from the condition or from antipsychotic medications, which are widely known to trigger Parkinson’s-like symptoms as a secondary side effect.

To determine whether medications explained the link, researchers excluded people who took antipsychotics from the analysis. They still found higher rates of Parkinson’s-related diagnoses in neurodivergent populations.

In the general population control group, the prevalence of parkinsonism was roughly 1.57%. The prevalence rose to 3.83% among adults with autism alone, 4.32% for those with an intellectual disability alone, and 4.86% among individuals diagnosed with both autism and an intellectual disability.

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"A critically important new contribution of this study is increased incidence rates of parkinsonism for autistic people in middle and older adulthood, which suggests that these cases aren’t simply a byproduct of lifelong motor challenges," Greg Wallace, lead author and a professor in the Department of Speech, Language and Hearing Sciences at The George Washington University in Washington, D.C., said in a press release.

The study represents the first time scientists have tracked the incidence rate, or the risk of newly emerging cases over time, among older autistic individuals.

"It is therefore important for clinicians to establish clear baselines of motor skills and challenges during adulthood that can be tracked over time," Wallace added.

Dr. Lee Murray, a neurologist based in Jackson, Tennessee, said this study clarifies previous research that suggested patients with autism are at a higher risk of having Parkinson's.

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"This study takes into account the use of antipsychotic medications that can cause a Parkinson's look (resting tremor, stiffness, shuffled gait, stooped posture, softened voice), which is a different pathology than stereotypical or idiopathic Parkinson's disease," Murray, who was not involved in the study, told Fox News Digital.

"This study showed patients with autism that was associated with intellectual disability seem to have the greatest association with concomitant Parkinson's."

The neurologist cautioned that autism encompasses a wide range of symptoms and severity, so the findings don't mean that people with milder cases face a significantly higher risk of Parkinson’s disease.

"It certainly is an interesting correlation, although it does not imply that someone with autism is certain to develop Parkinson's," Murray added.

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"From a clinical perspective, it's helpful to review medications with the autistic patient's physicians and, if possible, try to avoid medications that may cause a Parkinson's appearance."

Despite the scope of the data, the authors noted several key limitations of using insurance records.

The investigation relied on billing and diagnostic codes submitted through Medicare and Medicaid, which can contain errors or reflect differences in how clinics and medical providers diagnose conditions.

The reliance on claims data also means researchers could not assess the severity of individual motor symptoms or examine the role of lifestyle factors, genetics and family history, they noted.

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Additionally, the data only captured adults who were enrolled in public insurance programs, potentially leaving out older individuals who rely strictly on private health insurance.

Because people on the autism spectrum may already struggle with coordination, repetitive behaviors or executive functioning challenges, experts say early indicators of Parkinson’s disease can be missed or mistaken, potentially delaying essential care.

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"Patients with autism can have atypical movements that can be misdiagnosed as Parkinson's if the examiner is not accustomed to diagnosing it," Murray confirmed.

The researchers emphasized the need for physicians, long-term care facilities and family caregivers to closely monitor older autistic patients for motor decline so interventions can begin as early as possible.

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More Seven Year-Olds on Disability Benefits Than 50 Year-Olds Amid ADHD Surge

More seven year-olds are on disability benefits than 50 year-olds amid a surge in payouts for childhood ADHD and other mental health conditions, official figures show.

The post More Seven Year-Olds on Disability Benefits Than 50 Year-Olds Amid ADHD Surge appeared first on The Daily Sceptic.

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Rush to Diagnose ADHD and Autism is Damaging Children, Major Review Warns

Britain risks harming a generation of children by over-diagnosing ADHD and autism, a major review has warned, with autism diagnosis rates soaring by up to 40-fold despite no evidence of a genuine increase in prevalence.

The post Rush to Diagnose ADHD and Autism is Damaging Children, Major Review Warns appeared first on The Daily Sceptic.

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What Happens When a Kid’s Robot Best Friend Dies?

In this story for MIT Technology Review, Sara Harrison explores the field of social robotics and the growing use of robot companions as therapy for autistic and other neurodivergent kids. These playful machines show promise: Research suggests that they can help children practice social skills and offer something overworked therapists and exhausted parents can’t—a patient companion, available 24/7. But Harrison also reports on their limitations and risks. Does this approach truly work? What about all the data gathered on the child? And what happens when a robot friend suddenly stops working and “dies”? A fascinating and unsettling look at tech that has moved into the most intimate corners of a family’s home.

While Moxie found herself in more and more people’s homes, Embodied still struggled to make money. In 2024, the company announced it would cease operations. Its robots—which depended on external servers that the company could no longer pay for—would descend into a deep slumber. 

Videos of bereft children who seemed to have become deeply attached to the blue bot began to circulate online. “I don’t want her to leave,” wailed one child in a TikTok video. Desperate parents posted on TikTok, Instagram, and Reddit looking for solutions. “My autistic child is devastated and I’m pissed,” wrote one parent. “Hope Embodied gives us a couple days to say goodbye,” wrote another. 

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Meet Britain’s Hikikomori


Daniel left school five years ago and still lives with his parents—pretty normal in a country where around a third of young British men haven’t moved out. What is different about Daniel is his identification as “hikikomori”—literally “pulled inward”—a form of extreme social isolation. Since leaving school, he has left his family home “maybe once a month.” Research into hikikomori is limited, though some links with social anxiety and autism have been drawn. In this piece, Eve Livingston explores what day-to-day life is actually like for the families living with this phenomenon, doggedly seeking access to a world built to avoid in‑person encounters.

Dip your toe into the world of hikikomori, and you’ll find that attitudes vary widely, even among the self-identified. Some, like Daniel, display a level of sensitivity and sometimes defensiveness about their lifestyle, while others are more open about a sense of sadness and sometimes hopelessness they felt towards their circumstances. 

“I am [a hikikomori]… it sucks and I hate my life,” reads one such comment on Reddit. “Every single attempt at recovery has ended up in an even deeper relapse and its [sic] so painfully boring and lonely… I fantasise about being free all the time but I know I’m probably just going to die this way.”

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